![\"\u5fae\u4fe1\u622a\u56fe_20230601100053.png\"](\"https:\/\/www.whchip.com\/upload\/202306\/1685584879124823.png\" "\\"1685584879124823.png\\"")
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Application of Microfluidic Chip Technology in protein Analysis.<\/span><\/p>\n Protein is the most basic bioactive substance of organism. The separation and determination of protein can help people understand the role of protein in biological function and is of inestimable value in discovering new diagnosis and treatment methods.\u00a0<\/span>The traditional protein analysis steps are carried out by hand, these methods are too cumbersome, large sample consumption and low sensitivity, which can not meet the needs of proteomics for fast, integrated, high-throughput and high sensitivity analysis system.\u00a0<\/span>The microfluidic analysis chip system is used to analyze protein samples, protein structure, function and protein interaction. The analysis steps are carried out on a few square centimeters of analysis chip, with fast reaction speed and high sensitivity.\u00a0<\/span>In addition, the amount of reagents and reactants needed by microfluidic chip detection technology is less, which can greatly reduce the reagent consumption.\u00a0<\/span>Hofmann et al used isoelectric focusing capillary electrophoresis chip technology to label peptides with Cy5 to separate and detect the mixture of cytochrome C, ribonuclease An and myoglobin, and completed the whole detection process in 5 min.<\/span><\/p>\n <\/p>\n Application of Microfluidic Chip Technology in Cell Analysis.<\/span><\/p>\n With the rapid development of life science, the analysis and detection of the composition and morphological changes of single cell and intracellular has become the focus of research.\u00a0<\/span>Because the microchannel width (10 ~ 50 \u03bc m) of microfluidic chip is similar to that of biological cells, biological cells are easy to manipulate, observe and detect in microchannels. Single cell research with microfluidic chip has unique advantages.\u00a0<\/span>Shin et al. constructed a kind of electroporation cell chip. They carried out the electroporation experiment on the cells in the fluid channel through the exponential decay pulse generator, and measured various parameters of the cell electroporation.\u00a0<\/span>In recent years, a lot of studies have been carried out on the time and space control of chemical concentration gradient in cell microenvironment, cell culture and so on.\u00a0<\/span>It is believed that with the continuous update of microfluidic technology, this technology is expected to become the main tool for cell research.<\/span>[\/vc_column_text][\/vc_column][vc_column width=”1\/5″ rt_wrp_col_paddings=”false” rt_border_top=”” rt_border_bottom=”” rt_border_left=”” rt_border_right=”” rt_border_top_mobile=”” rt_border_bottom_mobile=”” rt_border_left_mobile=”” rt_border_right_mobile=”” rt_bg_image_repeat=”repeat” rt_bg_size=”auto auto” rt_bg_position=”right top” rt_bg_attachment=”scroll”][vc_widget_sidebar sidebar_id=”sidebar-for-portfolio”][\/vc_column][\/vc_row]<\/p>\n","protected":false},"excerpt":{"rendered":" [vc_row rt_row_background_width=”default” rt_row_style=”default-style” rt_row_borders=”” rt_row_paddings=”true” rt_bg_effect=”classic” rt_bg_image_repeat=”repeat” rt_bg_size=”cover” rt_bg_position=”right top” rt_bg_attachment=”scroll” rt_bg_video_format=”self-hosted”][vc_column width=”4\/5″ rt_wrp_col_paddings=”false” rt_border_top=”” rt_border_bottom=”” rt_border_left=”” rt_border_right=”” rt_border_top_mobile=”” rt_border_bottom_mobile=”” rt_border_left_mobile=”” rt_border_right_mobile=”” rt_bg_image_repeat=”repeat” rt_bg_size=”auto auto” rt_bg_position=”right top” rt_bg_attachment=”scroll”][vc_column_text]Microfluidic technology is regarded as one of the most capable technologies to change human beings in the 21st century, and its main application field is the biomedical field […]<\/p>\n","protected":false},"author":1,"featured_media":5106,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"yoast_head":"\n