{"id":4886,"date":"2021-12-24T16:34:06","date_gmt":"2021-12-24T08:34:06","guid":{"rendered":"http:\/\/43.135.177.8\/?p=4886"},"modified":"2021-12-24T16:36:10","modified_gmt":"2021-12-24T08:36:10","slug":"skin-interfaced-microfluidic-system-with-personalized-sweating-rate-and-sweat-chloride-analytics-for-sports-science-applications","status":"publish","type":"post","link":"https:\/\/whmicro.com\/?p=4886","title":{"rendered":"Skin-interfaced microfluidic system with personalized sweating rate and sweat chloride analytics for sports science applications"},"content":{"rendered":"

[vc_row rt_row_background_width=”default” rt_row_style=”default-style” rt_row_borders=”” rt_row_paddings=”true” rt_bg_effect=”classic” rt_bg_image_repeat=”repeat” rt_bg_size=”cover” rt_bg_position=”right top” rt_bg_attachment=”scroll” rt_bg_video_format=”self-hosted”][vc_column width=”4\/5″ rt_wrp_col_paddings=”false” rt_border_top=”” rt_border_bottom=”” rt_border_left=”” rt_border_right=”” rt_border_top_mobile=”” rt_border_bottom_mobile=”” rt_border_left_mobile=”” rt_border_right_mobile=”” rt_bg_image_repeat=”repeat” rt_bg_size=”auto auto” rt_bg_position=”right top” rt_bg_attachment=”scroll”][vc_column_text]<\/p>\n

Soft wearable microfluidic patch design and sensing strategies<\/h3>\n
The wearable microfluidic patch technology introduced here involves multilayered stacks of thin-film polymers that contain intricate microfluidic channels created using laser and die cutting techniques. The network of microchannels and assay wells are created using roll-to-roll processing of polymeric rolls of materials, allowing for rapid (~1000 patches\/min) and low-cost manufacturing of soft conformal microfluidic constructs, as an alternative to silicone-based mold casting techniques. The microfluidic channels are composed of hydrophobic polymeric materials that route sweat by exploiting the natural pressure associated with eccrine sweat excretion.\u00a0Figure 1A<\/a>\u00a0shows the multilayered microfluidics, dye and bioassay reservoirs, the top graphics layer with color reference stripes, and a subjacent skin adhesive layer, which collectively define the low-modulus features of the flexible sticker-like patch. Microchannel 1 has the capacity to collect ~130 \u03bcl of sweat from a defined sweat collection region (38.5 mm2<\/sup>\u00a0and 7 mm diameter). An orange dye mixes with sweat to make propagation along the channel highly visible, allowing rapid assessment and measurement of sweat volume (Fig. 1A<\/a>, inset). In contrast, microchannel 2 has a smaller capacity (~30 \u03bcl) and collection area (12.6 mm2<\/sup>\u00a0and 4 mm diameter) designed to support a colorimetric reaction between excreted sweat entering the microchannel and deposited chemical reagents for analysis of [Cl\u2212<\/sup>].\u00a0Figure 1B<\/a>\u00a0shows a representative example of the microfluidic patch (without the top graphics layer) skin-mounted on the ventral forearm before exercise begins. During exercise, microchannels 1 and 2 capture and mix sweat as shown in\u00a0Fig. 1C<\/a>. The spatial extent of orange sweat capture in microchannel 1 and the purple color intensity in microchannel 2 provide a measure of local sweat excretion volume and sweat [Cl\u2212<\/sup>], respectively.\u00a0Figure 1D<\/a>\u00a0shows an optical image of the microfluidic patch on another subject with defined vein contours on the ventral forearm. The microfluidic patch intimately conforms to the surface of the skin without causing irritation around curvilinear regions or in the presence of heavy sweat excretion. The thin geometry (~680 \u03bcm) and low bending stiffness of the device support mechanical deformations (Fig. 1E<\/a>), aiding wearability during intense physical activities.<\/div>\n
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<\/figure>\n<\/div>\n

Please refer to the original article:<\/a>[\/vc_column_text][\/vc_column][vc_column width=”1\/5″ rt_wrp_col_paddings=”false” rt_border_top=”” rt_border_bottom=”” rt_border_left=”” rt_border_right=”” rt_border_top_mobile=”” rt_border_bottom_mobile=”” rt_border_left_mobile=”” rt_border_right_mobile=”” rt_bg_image_repeat=”repeat” rt_bg_size=”auto auto” rt_bg_position=”right top” rt_bg_attachment=”scroll”][vc_widget_sidebar sidebar_id=”sidebar-for-portfolio”][\/vc_column][\/vc_row]<\/p>\n","protected":false},"excerpt":{"rendered":"

[vc_row rt_row_background_width=”default” rt_row_style=”default-style” rt_row_borders=”” rt_row_paddings=”true” rt_bg_effect=”classic” rt_bg_image_repeat=”repeat” rt_bg_size=”cover” rt_bg_position=”right top” rt_bg_attachment=”scroll” rt_bg_video_format=”self-hosted”][vc_column width=”4\/5″ rt_wrp_col_paddings=”false” rt_border_top=”” rt_border_bottom=”” rt_border_left=”” rt_border_right=”” rt_border_top_mobile=”” rt_border_bottom_mobile=”” rt_border_left_mobile=”” rt_border_right_mobile=”” rt_bg_image_repeat=”repeat” rt_bg_size=”auto auto” rt_bg_position=”right top” rt_bg_attachment=”scroll”][vc_column_text] Soft wearable microfluidic patch design and sensing strategies The wearable microfluidic patch technology introduced here involves multilayered stacks of thin-film polymers that contain intricate microfluidic channels created […]<\/p>\n","protected":false},"author":1,"featured_media":4887,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[100],"yoast_head":"\nSkin-interfaced microfluidic system with personalized sweating rate and sweat chloride analytics for sports science applications - 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